The genome is fixed. Its activity is not.
Our genes contain the biological instructions used by cells, but not every gene is active all the time. Epigenetics looks at the systems that influence which instructions are read and when.
The epigenome is dynamic. UV exposure, pollution, stress and ageing can influence cellular signalling connected with melanin production, inflammatory mediators and the proteins that support skin structure.
Three useful concepts
DNA methylation adds small chemical markers that can affect gene activity. Histone modification changes how tightly DNA is packaged and therefore how accessible a section is. MicroRNA helps regulate how much of a particular protein is produced.
- DNA methylation: markers that influence gene activity
- Histones: proteins that help package and reveal DNA
- MicroRNA: small regulators of protein production
What this means for cosmetic care
Modern cosmetic actives may be selected for their effect on pathways associated with pigmentation, oxidative stress and visible renewal. It is more accurate to speak about supporting or modulating these pathways than about changing a person’s genes.
Exo Bright Lumina combines this approach with exfoliating, antioxidant and barrier-supportive ingredients to address uneven-looking tone from several directions.